From established gamers to up-and-coming companies, Canada’s pharmaceutical firm panorama is various and dynamic.
Canadian drug firms are working to find and develop main improvements amidst an more and more aggressive international panorama. Rising applied sciences corresponding to synthetic intelligence are taking part in a task within the panorama as properly.
Right here the Investing Information Community lists the highest Canadian pharma shares on the TSX, TSXV and CSE by year-over-year good points. All information was compiled on January 10, 2025, utilizing TradingView’s stock screener, and firms with market caps above C$10 million at the moment had been thought-about.
Learn on to find out about what’s been driving the share costs of the very best performing Canadian pharma shares.
1. NurExone Biologic (TSXV:NRX)
Yr-over-year acquire: 147.27 %
Market cap: C$34.08 million
Share value: C$0.68
NurExone Biologic is the biopharmaceutical firm behind ExoTherapy, a drug supply platform that makes use of exosomes, that are nano-sized extracellular vesicles, to create therapies for central nervous system problems, spinal twine accidents and traumatic mind accidents. It’s a much less invasive various to cell transplantation, which requires surgical procedure and carries the chance of rejection.
NurExone’s first nano-drug, ExoPTEN, makes use of a proprietary sIRNA sequence delivered with the ExoTherapy platform to deal with spinal twine accidents. ExoPTEN received orphan drug designation from the US Meals and Drug Administration (FDA) in October 2023, that means it has been acknowledged as a possible therapy for uncommon medical circumstances. The designation makes it eligible for incentives corresponding to market exclusivity and regulatory help geared toward accelerating its improvement and approval.
In December 2024, the corporate launched preclinical results from animal testing evaluating the efficacy of its nano-drug ExoPTEN in restoring misplaced imaginative and prescient. The lead investigator on the Goldschleger Eye Institute, which collaborated on the examine, stated the outcomes had been “extraordinarily encouraging,” and “counsel that ExoPTEN might basically change how we strategy circumstances like glaucoma and optic nerve trauma.”
2. Cipher Pharmaceuticals (TSX:CPH)
Yr-over-year acquire: 140.88 %
Market cap: C$377.18 million
Share value: C$14.26
Cipher Prescription drugs is a specialty pharma firm with a various portfolio of therapies, together with a variety of dermatology and acute hospital care merchandise. The corporate has out-licensed a few of its choices as properly. Cipher began trading on the OTCQX Best Market underneath the image CPHRF in early 2024.
Along with its present portfolio, Cipher has acquired Canadian rights to CF-101, a dermatology therapy for average to extreme plaque psoriasis is at present anticipated to endure Section III scientific trials. The corporate can also be conducting proof-of-concept research on DTR-001, a topical therapy for eradicating tattoos.
On July 29, Cipher introduced it had signed a definitive asset purchase agreement with ParaPRO for its US-based Natroba operations and international product rights, and the information precipitated Cipher’s share value to spike considerably. The corporate’s Q3 2024 results confirmed a product gross margin from the acquired Natroba merchandise of 85 %.
3. Satellos Bioscience (TSXV:MSCL)
Yr-on-year acquire: 88.89 %
Market cap: C$95.99 million
Share value: C$0.85
Satellos Bioscience is a Canadian pharmaceutical firm increasing therapy choices for muscle problems. The corporate has centered particularly on Duchenne muscular dystrophy, creating therapies to regenerate and restore muscle tissue by focusing on the precise organic pathways concerned. Its lead candidate SAT-3247 targets a protein known as AAK1, which regulates the exercise of stem cells that activate and differentiate new muscle fibers.
An acceptance to commence Phase 1 clinical trials of the drug was introduced on August 19 and the first patient was dosed on September 18. Evaluation of tests conducted on canines, shared on October 1, confirmed improved muscle morphology and elevated muscle regeneration with no opposed unwanted side effects.
An update was offered in November, revealing it had begun enrolment for a multiple-ascending-dose arm of the Section 1 examine after no drug-related opposed occasions had been reported within the single-ascending-dose group.
4. Telescope Innovations (CSE:TELI)
Yr-over-year acquire:81.4 %
Market cap: C$20.39 million
Share value: C$0.39
Telescope Improvements is a chemical expertise firm that develops scalable manufacturing processes and instruments that mix robotic automation, on-line evaluation and machine studying for the pharmaceutical and chemical industries.
The corporate has commercialized its Direct Inject-LC system. Quick for Direct Inject Liquid Chromatography, the system combines {hardware} and software program to research chemical reactions and might probably scale back the time and price of latest drug improvement.
On July 31, Telescope Improvements entered right into a collaborative analysis settlement with pharma large Pfizer (NYSE:PFE) to speed up pharmaceutical analysis and improvement utilizing automation, robotics and synthetic intelligence.
In accordance with a press release, some efforts will deal with deploying Self-Driving Laboratories, an idea pioneered by Telescope Improvements during which robotic programs perform experiments whereas AI algorithms analyze the information in actual time to tell researchers about what the following steps needs to be.
5. Medexus Pharmaceuticals (TSX:MDP)
Yr-over-year acquire: 46.47 %
Market cap: C$100.34 million
Share value: C$3.94
Medexus Prescription drugs focuses on bringing medicine to deal with uncommon illnesses to North America. The corporate manages all the course of by means of its absolutely built-in operations, from buying and creating medicine to advertising and promoting them. A few of its key merchandise embody therapies for hemophilia B and rheumatoid arthritis, in addition to a line of medicine for autoimmune illnesses like lupus and allergy therapies.
In November 2024, Medexus Prescription drugs announced it had efficiently negotiated with the pan-Canadian Pharmaceutical Alliance to make treosulfan, which Medexus commercialized in Canada underneath the identify Trecondyv, accessible to publicly funded drug packages and sufferers. Trecondyv is indicated as a part of conditioning therapy previous to bone marrow transplants in sufferers with sure varieties of blood cancers.
Along with Canada, Medexus has the unique commercialization rights to treosulfan within the US, the place it at present being reviewed by the FDA for approval. The FDA extended the review period for the brand new drug utility for treosulfan in September and set a brand new prescription drug consumer charge act goal motion date of January 30, 2025.
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Securities Disclosure: I, Meagen Seatter, maintain no direct funding curiosity in any firm talked about on this article.
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